| Category | Player | Team | Stat |
| Games | Phil Bradley | Seattle | 162 |
| At Bats | Devon White | California | 693 |
| Runs Scored | Kirby Puckett | Minnesota | 157 |
| Hits | Alan Trammell | Detroit | 263 |
| Doubles | Paul Molitor Alvin Davis | Milwaukee Seattle | 47 |
| Triples | Tony Fernandez | Toronto | 15 |
| Home Runs | George Bell | Toronto | 56 |
| RBI | George Bell | Toronto | 185 |
| Batting Average | Tony Fernandez | Toronto | .396 |
| Total Bases | Kirby Puckett | Minnesota | 444 |
| Slugging Percentage | George Bell | Toronto | .712 |
| Stolen Bases | Phil Bradley Harold Reynolds | Seattle | 102 |
| Caught Stealing | Harold Reynolds | Seattle | 19 |
| Sacrifice Hits | Harold Reynolds | Seattle | 9 |
| SacrificeFlies | Harold Reynolds | Seattle | 10 |
| Strikeouts | Larry Parrish | Texas | 178 |
| Bases On Balls | Wade Boggs | Boston | 130 |
| Intentional BB | George Bell | Toronto | 18 |
| Hit By Pitch | Don Baylor | Boston/Minnesota | 25 |
| On-Base Pct. | Wade Boggs | Boston | .484 |
| Total Average | Paul Molitor | Milwaukee | 1.426 |
| Runs Contributed | Kirby Puckett | Minnesota | 98.3 |
| Runs Created | Mark McGuire | Oakland | 195.7 |
| Runs Created/Game | Paul Molitor | Milwaukee | 14.0 |
| Hitting Streak | Marty Barrett Pat Tabler | Boston Cleveland | 19 |
| Grounded Into DP | Jim Rice Frank White | Boston Kansas City | 27 |
| OF Assists | Dave Winfield | New York | 29 |
| Passed Balls | Jamie Quirk | Kansas City | 19 |
| Category | Pitcher | Team | Stat |
| Appearances | Mark Eichhorn | Toronto | 86 |
| Games Started | Charlie Hough | Texas | 40 |
| Complete Games | Roger Clemens | Boston | 18 |
| Games Finished | Tom Henke | Toronto | 63 |
| Innings Pitched | Charlie Hough | Texas | 301.1 |
| Wins | Jimmy Key | Toronto | 27 |
| Losses | Al Nipper | Boston | 18 |
| Won/Loss Pct. | Jimmy Key | Toronto | .900 |
| Runs Surrendered | Ken Schrom | Cleveland | 156 |
| Earned Runs Surrendered | Ken Schrom | Cleveland | 142 |
| Hits Allowed | Tom Candiotti | Cleveland | 267 |
| Home Runs | Floyd Bannister | Chicago | 45 |
| Strikeouts | Roger Clemens | Boston | 260 |
| Bases On Balls | Dave Stewart | Oakland | 111 |
| Intentional BB | Dale Mohorcic | Texas | 11 |
| Batsmen Faced | Charlie Hough | Texas | 1214 |
| Opponents Batting Avg | Frank Viola | Minnesota | .173 |
| Shutouts | Mark Langston | Seattle | 6 |
| Saves | Tom Henke | Toronto | 38 |
| Blown Saves | Tom Henke | Toronto | 12 |
| Holds | Mark Eichhorn | Toronto | 26 |
| ERA | Frank Viola | Minnesota | 2.16 |
| Quality Starts | Frank Viola | Minnesota | 26 |
| Wild Pitches | Tom Candiotti | Cleveland | 12 |
| Hit Batsmen | Frank Tanana | Detroit | 11 |
| Balks | Bill Long | Chicago | 3 |